Showing posts with label Mange. Show all posts
Showing posts with label Mange. Show all posts

Friday, February 21, 2020

Sarcoptic Mange in Dogs

What causes sarcoptic mange?
Sarcoptic mange is caused by a parasitic mite (Sarcoptes scabiei) that burrows just beneath the surface of the skin. It is important not to confuse sarcoptic mange with demodectic mange, which is caused by a different parasitic mite.
"Sarcoptic mange is a zoonotic disease or a disease transmissible from pets to people."
These mites bury into the skin of healthy adult dogs and puppies, and feed on material in and on the skin. Sarcoptic mange is also known as scabies and is zoonotic, which means it is a disease transmissible from pets to people.

What does it do to the dog?
The presence of the sarcoptic mite causes intense itching. The dog will chew and scratch its skin constantly. This leads to the loss of large amounts of hair, especially on the legs and belly. Eventually, the skin will become thickened and will darken.

Is it contagious?
Yes. Sarcoptic mange is highly contagious to other dogs and humans.
Although sarcoptic mites are not able to complete their life cycle on humans, they will cause severe itching until they die. Since the mite may be found in areas where infected dogs or foxes frequent, keep your dog away from these areas to attempt to prevent infection.

How is sarcoptic mange diagnosed?
Diagnosis is made by a skin scraping examined under the microscope. It is common not to see sarcoptic mange mites when performing a skin scraping. This is because the mites burrow deep into the skin and it takes only a few mites to cause significant itching.
Just because no mites are seen, does not mean your dog does not have sarcoptic mange. A presumptive diagnosis may therefore be made, based on clinical signs. Sarcoptic mange may occur in any dog at any age.

How is it treated?
There are several medications that are effective against Sarcoptes. Your veterinarian will discuss the best treatment for your pet's condition and lifestyle. Treatment varies from medicated baths and dips to injections and oral medications. Many pets will require a combination of treatments to resolve this infection.

Topical treatments may be divided into two categories:
1)   Dips. Some of the dips that are used to treat Sarcoptes include amitraz and lime-sulfur dip. Your veterinarian will provide you with information on how to use these dips.
2)   Topicals. Medication applied topically to one or two spots while the animal is dry. These medications are applied every 14-30 days or as your veterinarian recommends. Some examples of these topical medications include selamectin, imidacloprid and moxidectin, fipronil among many others.

Just like topical medications, there are a wide variety of oral medications available for the treatment of sarcoptic mange. These oral medications may be prescribed in the form of liquid, pill, or flavored chew, depending on the medication prescribed. Some of these oral medications include milbemycin (the active ingredient of Interceptor® and Sentinel®), afoxolaner (NexGard®), fluralaner (Bravecto®), and sarolaner (Simparica®). These medications are used 'off label' for the treatment of sarcoptic mange. The term 'off label' describes the use of a drug for conditions other than what it was approved for. Many of these medications are given for multiple treatments. To prevent re-infection, discard any bedding where your dog sleeps, or wash it frequently in diluted bleach solution (one ounce bleach in one gallon of water). If you dog is still scratching four to five days after treatment has started, please contact your veterinarian.

Can I get mange from my dog?
Yes. If any member of the family develops itching or a skin rash, contact your family doctor immediately. Tell your doctor that you may have been exposed to sarcoptic mange or scabies. In people, the mite cannot complete its life cycle so it will die in a few days. However, it may cause intense itching during that time and medical treatment is often recommended.

By Ernest Ward, DVM; Updated by Amy Panning, DVM
Contributors: Ernest Ward, DVM; Updated by Amy Panning, DVM
© Copyright 2018 LifeLearn Inc. Used and/or modified with permission under license.


Demodectic Mange in Dogs

Mange is a parasitic skin disease caused by microscopic mites. Two different mange mites cause skin disease in dogs. One lives just under the surface of the skin (sarcoptic mange), while the other resides in the hair follicles (demodectic mange). Although both mites share similar characteristics, there are also important differences. It is important not to confuse the two types of mange because they have different causes, treatments, and prognoses.

What causes demodectic mange?
Demodectic mange is caused by Demodex canis, a parasitic mite that lives in the hair follicles of dogs. Under the microscope, this mite is shaped like a cigar with eight legs. Demodectic mange, sometimes just called ‘demodex’ or ‘red mange’, is the most common form of mange in dogs.
"As long as the body's immune system is functioning properly, these mites cause no harm."
All normal dogs (and many humans) have a few of these mites on their skin. As long as the body's immune system is functioning properly, these mites cause no harm.

Demodectic mange most often occurs when a dog has an immature immune system, allowing the number of skin mites to increase rapidly. As a result, this disease occurs primarily in dogs less than 12 to 18 months of age. As the dog matures, its immune system also matures.

Adult dogs that have the disease usually have weakened immune systems. Demodectic mange may occur in older dogs because function of the immune system often declines with age. Dogs who have a weakened immune system due to illness or certain medications are also susceptible to demodectic mange.

Is demodectic mange contagious?
No, demodectic mange is not contagious to other animals or humans. Demodex mites are transmitted to puppies from their mother during the first few days of life. Since the mite is found on virtually all dogs, exposure of a normal dog to one with demodectic mange is not dangerous, as the immune system must be depressed for mange to develop.
"Demodectic mange is not contagious to other animals or humans."

Why doesn't the immune system mature correctly in some dogs?
Development of the immune system is under genetic or hereditary control. An affected dog often has littermates that are also affected. Owners of littermates should be alerted to watch for the development of mange in their puppies. Because the disease is due to a genetic defect, affected dogs should not be bred, and the parents of the affected dog should not be bred again.
What does demodectic mange do to the dog?

Surprisingly, a dog with demodectic mange usually does not itch severely, even though it loses hair in patches. The hair loss usually begins on the face, especially around the eyes. When there are only a few patches of hair loss, the condition is called localized demodectic mange. If the disease spreads to many areas of the skin, the condition is called generalized demodectic mange.

How is demodectic mange diagnosed?
"Your veterinarian will take deep skin scrapings and examine them under the microscope to diagnose this disease."
Your veterinarian will take deep skin scrapings and examine them under the microscope to diagnose this disease. The finding of larger than normal numbers of Demodex mites in skin scrapings confirms the diagnosis. Occasionally, the disease will be diagnosed by means of a skin biopsy in dogs that have chronic skin infections that have not responded appropriately to treatment.

How is demodectic mange treated?
The localized form is usually treated with topical medication. The generalized form requires more aggressive treatment using special shampoos and dips, along with oral medication. Shampooing with special cleansing shampoos containing benzoyl peroxide helps to flush out and open the hair follicles prior to dipping. 

There are also several 'spot on' topical treatments, such as imidacloprid and moxidectin. These medications are used 'off label' for the treatment of demodicosis. The term 'off label' describes the use of a drug for conditions other than what it was approved for.

There is an injectable form of doramectin, which can also be used for off label treatment of demodex. Your veterinarian will discuss the benefits and risks of these medications with you.

In some cases, especially dogs with generalized demodectic mange, secondary skin infections complicate the condition, requiring antibiotic therapy. Because dogs with skin infections often have very red, inflamed skin, demodectic mange is often called ‘red mange’. Your veterinarian can help you determine whether or not your dog has a skin infection in addition to demodectic mange.

Are there any problems with topical treatment?
The dip commonly used for demodectic mange contains the insecticide amitraz. It must be used very carefully because it is a strong insecticide that can cause serious side effects, both to your dog and to you, if not used properly. Your dog may experience vomiting and sedation for twenty-four to thirty-six hours following each application. Most of these problems will resolve without medical intervention. If your dog reacts in this manner, you should dilute the next dip with 25% more water. If you are using a ‘spot on’ topical treatment, you may see drooling if your dog licks the medication.
"Amitraz must be used very carefully because it is a strong insecticide that can cause serious side effects, both to your dog and to you, if not used properly."
Since most dogs develop tolerance to the dip as they are repeated, your dog is less likely to have side effects with each subsequent treatment. After receiving two to three dipping treatments at seven-day intervals, skin scrapings should be repeated and examined for the presence of live mites or mite eggs. The results of these skin scrapings will determine whether further treatment is needed.

I heard that there is a drug that can be given orally for demodectic mange. Is that true?
Yes, under certain conditions.

Ivermectins are a class of drugs that are approved for prevention of heartworm disease in dogs and cats. Certain ivermectins are used to treat parasites on cattle. The cattle preparation has been used orally for demodectic mange in some dogs. However, ivermectin is not approved for use in treating dogs with mange, so its use to treat mite infestations in dogs is off-label.

Ivermectin is a very strong drug that can cause severe side-effects, including death, if it is not administered properly. It is extremely important to follow your veterinarian’s instructions and cautions carefully, as their directions may be very different from those on the label. Veterinarians do not generally recommend ivermectin for use in Collies, Shetland Sheepdogs, Australian Shepherds, Old English Sheepdogs, or any other herding breed because they are sensitive to the medication.
There are a few other oral medications that may be used off label in the treatment of the demodex mite. These include milbemycin oxime (the active ingredient of Interceptor® and Sentinel®), afoxolaner (NexGard®), and fluralaner (Bravecto®). Your veterinarian will help you decide which oral or topical medication is best for your dog.

What is the prognosis for my dog?
Treatment of demodectic mange is generally successful. However, if the immune system is weakened, neither the mites nor the infection may respond to treatment. With generalized demodicosis, successful treatment may take a long time, and may require regular skin scrapings to check the progress of the treatment.

Following successful treatment, is it likely to recur?
"It is important to treat as soon as a relapse occurs to minimize the possibility of developing uncontrollable problems."
Because the immune system does not mature until 12 to 18 months of age, a dog with demodectic mange may have relapses until that age. In addition, dogs with suppressed immune systems may be susceptible to relapse. It is important to treat as soon as a relapse occurs to minimize the possibility of developing uncontrollable problems. Relapses are usually recognized 3-6 months after treatment is discontinued.

By Ernest Ward, DVM; Updated by Amy Panning, DVM
Medical Conditions, Parasites, Pet Services
https://vcahospitals.com/know-your-pet/mange-demodectic-in-dogs

Contributors: Ernest Ward, DVM; Updated by Amy Panning, DVM
© Copyright 2018 LifeLearn Inc. Used and/or modified with permission under license.

Tuesday, June 9, 2015

Mange in dogs!



Mange - Demodectic in Dogs

Mange is a parasitic skin disease caused by microscopic mites. Two different mange mites cause skin disease in dogs. One lives just under the surface of the skin, while the other resides deep in the hair follicles. Although both mites share similar characteristics, there are also important differences. It is important not to confuse the two types of mange because they have different causes, treatments, and prognoses.

What causes demodectic mange?
 Demodectic mange, sometimes just called "demodex" or "red mange", is the most common form of mange in dogs. It is caused by the Demodex canis, a parasite that lives in the hair follicles of dogs. Under the microscope, this mite is shaped like a cigar with eight legs. 

"As long as the body's immune system is functioning properly, these mites cause no harm. "
All normal dogs (and many humans) have a few of these mites on their skin. As long as the body's immune system is functioning properly, these mites cause no harm.
Demodectic mange most often occurs when a dog has an immature immune system, allowing the number of skin mites to increase rapidly. As a result, this disease occurs primarily in dogs less than twelve to eighteen months of age. As the dog matures, its immune system also matures. Adult dogs that have the disease usually have defective immune systems. Demodectic mange may occur in older dogs because function of the immune system often declines with age. Dogs who have immune suppression due to illness or certain medications are also candidates for demodectic mange.

Is demodectic mange contagious?
"Demodectic mange is not contagious to other animals or humans."
No, demodectic mange is not contagious to other animals or humans. Demodex mites are transmitted to puppies from their mother during the first few days of life. Since the mite is found on virtually all dogs, exposure of a normal dog to one with demodectic mange is not dangerous.
If your dog is showing these symptoms do not wait for the mange to spread. It's better to contact your Veterinarian.

Why doesn't the immune system mature correctly in some dogs?
Development of the immune system is under genetic or hereditary control. Thus, an affected dog often has littermates that are also affected. Owners of littermates should be alerted to watch for the development of mange in their puppies. Because the disease is due to a genetic defect, affected dogs should not be bred, and the parents of the affected dog should not be bred again.

What does demodectic mange do to the dog?
Surprisingly, a dog with demodectic mange usually does not itch severely, even though it loses hair in patches. The hair loss usually begins on the face, especially around the eyes. When there are only a few patches of hair loss, the condition is called localized demodectic mange. If the disease spreads to many areas of the skin, it becomes generalized demodectic mange.

How is demodectic mange diagnosed?
"Your veterinarian will take deep skin scrapings and examine them under the microscope to diagnose this disease."

Your veterinarian will take deep skin scrapings and examine them under the microscope to diagnose this disease. The finding of larger than normal numbers of Demodex mites in skin scrapings confirms the diagnosis. Occasionally, the disease will be diagnosed by means of a skin biopsy in dogs that have chronic skin infections that have not responded appropriately to treatment.

How is demodectic mange treated?
The localized form is usually treated with topical medication. The generalized form requires more aggressive treatment using special shampoos and dips, along with oral medication. Shampooing with special cleansing shampoos containing benzoyl peroxide helps to flush out and open the hair follicles prior to dipping. A separate handout is available to describe the dipping process. In some cases, especially dogs with generalized demodectic mange, secondary skin infections complicate the condition, requiring antibiotic therapy. Dogs with skin infections often have very red, inflamed skin. This is the source of the term "red mange."

Are there any problems with topical treatment?
The dip commonly used for demodectic mange contains the insecticide amitraz. It must be used cautiously because it is a strong insecticide that can cause side effects, both to your dog and to you, if not used properly. Your dog may experience vomiting and sedation for twenty-four to thirty-six hours following each application. Most of these problems are self-limiting and resolve without medical intervention. If your dog reacts in this manner, you should dilute the next dip with 25% more water. Since most dogs develop tolerance to the dip as they are repeated, your dog is less likely to have side effects with each subsequent treatment. After receiving two to three dipping treatments at seven-day intervals, skin scrapings should be repeated and examined for the presence of live mites or mite eggs. The results of these skin scrapings will determine whether further treatment is needed.

I heard that there is a drug that can be given orally for demodectic mange. Is that true?
Yes, under certain conditions.

Ivermectins are a class of drugs that are approved for prevention of heartworm disease in dogs and cats. Milbemycin oxime, the active ingredient of Interceptor® and Sentinel® heartworm preventives, may be used to treat demodicosis in certain cases. Certain ivermectins are used to treat parasites on cattle. In the past, the cattle preparation has been used orally for demodectic mange in some dogs. However, it is a very strong drug that can cause severe side-effects, including death, if it is not administered properly. It is not approved for use in dogs, so we would only consider using it as long as you are willing to accept liability for adverse effects. Veterinarians do not generally recommend ivermectin usage in collies, Shetland sheepdogs, Australian shepherds, old English sheepdogs, or any other herding breed.

What is the prognosis for my dog?
Treatment of demodectic mange is generally successful. However, if the immune system is defective, neither the mites nor the infection may respond to treatment. With generalized demodicosis, successful treatment may take a long time.

Following successful treatment, is it likely to recur?
"It is important to treat as soon as a relapse occurs to minimize the possibility of developing uncontrollable problems."

Because the immune system does not mature until twelve to eighteen months of age, a dog with demodectic mange may have relapses until that age. It is important to treat as soon as a relapse occurs to minimize the possibility of developing uncontrollable problems.

This client information sheet is based on material written by: Ernest Ward, DVM